The town has been actively settled since the times of the Umbri. It has been under the successive domination of the Romans, Lombards, being called Coccorone in the Middle Ages. In 1249 it was sacked by Frederick II, but was soon rebuilt with the modern name. from the 13th century it had been a free comune under the domination of local nobles and merchants, but later, as with many other Umbrian locales, the comune gave way to government by a Signoria in this case, that of the Trinci from the nearby Foligno (1383–1439). In 1446 it fell under the rule of the Papal States where it remained until the unification of Italy in 1861. St. Clare of Montefalco, sometimes known as St. Clare of the Cross, was born in Montefalco and died there in 1308. Montefalco today has several churches, some in the Romanesque, some in the Gothic and some in the Renaissance style. Historically, the most important is the church of San Francesco, which is now the town’s museum, and, given its collection of art and artifacts, one of the most important museums in Umbria. The church is notable for its fresco cycle on the life of St. Francis, by the Florentine artist Benozzo Gozzoli (1450–1452). Other artists represented in the museum include Perugino, Francesco Melanzio, Pier Antonio Mezzastris, Antoniazzo Romano and Tiberio d’Assisi. Among the other churches found inside and outside the town walls are Sant’Agostino, Santa Clara, Santa Illuminata and San Fortunato, the latter, built in the 4th century over the tomb of Fortunatus of Spoleto and renovated in the 15th century, had frescoes by Gozzoli and Tiberio d’Assisi. The 13th century Palazzo Comunale (“Town Hall”) has a mullioned window from the original edifice and a 15th-century portal. Also notable are the gates in the walls, including Porta Sant’Agostino, Porta Camiano and Porta Federico II. The comune of Montefalco and a small area of the comune of Bevagna constitute the regulated geographical area for Montefalco wines. Every year around Easter, the town sponsors a major festival called Settimana Enologica or Wine Week where visitors can enjoy the principal wines produced in the area including the comparatively simple red table wine, Montefalco Rosso, the more complex DOCG red wines Sagrantino, for which the area is famous, and the Montefalco Sagrantino secco.